News

April 3, 2021

“It’s always darkest before dawn”… one of those sentences that’s used in the context of “As bad as things seem, they’ll always get better.”

Pragmatically, it’s not really true… for numerous reasons. At the most superficial level, we live in a world of artificial light… and if you’ve ever been out in the street at dawn, right at the moment the streetlights switch off, you may have noticed that the little bit of sun doesn’t actually make up for all the acetylene or halogen or neon or argon or sodium vapour or whatever lighting that just disappeared. And even if you’re out in the middle of nowhere, there are stars and the moon, which themselves can be bright and offer light… and whose brightness fades when the sun begins to emerge. I guess if it’s pitch black and then that first photon of sunlight appears over the eastern horizon, this would hold true… but there are too many other variables.

If you assume the end of this pandemic is sunrise, we’re in more darkness today than we might have thought a month ago. It’s hard to plan for the sunrise if you don’t know where you are, nor what time of the year it is. The darkness-to-full-sunshine in Costa Rica in July (around 20 minutes) is a different experience than being in northern Finland in late December. Dress warm; you’ll be waiting a long time.

Waiting for the end of this pandemic is like that… but where, geographically, we change locations every day. And date. And, just for fun, the earth slows down and speeds up without telling anyone.

Variants, transmission events, uneven vaccine rollouts, anti-vaxxers, politics… these are all independent variables in a formula that’s unsolvable because there are other variables too, and we don’t even know what they are.

In the meantime, locally, it’s gotten a bit darker. Numbers are up. The majority of people getting sick are younger… and that now includes the majority of our Vancouver Canucks. These guys are among the healthiest people around, yet some of them are concerningly ill and receiving IV treatment. And, in the midst of these concerning new variables, a protest was organized yesterday at 2pm at City Hall… small business owners protesting the recent 3-week restrictions.

I certainly understand their frustration. They want the sun to rise too, but it’s elusive. The rules seem arbitrary… and seem to change overnight. How can anyone plan for anything?

I have no problem with business owners protesting/advocating for what they perceive to be their best interests.

I have a huge effing problem, however, in seeing that the vast majority of those protestors, all standing close to each other, yelling and chanting and whatever else… were not wearing masks. It boggles the mind, and I would hope the irony is not lost on them. “If only there were a way to open up sooner”, they masklessly commiserate with each other. “If only people realized that restaurants aren’t the problem”, they masklessly voice loudly into each other’s faces.

More than 1,000 new cases each of the last two days. And as the news will be reporting tomorrow, Canada has just gone over 1,000,000 cases.

In the meantime, the long night rolls on… and the horizon, distant as it is, has yet to start spilling over some much-needed sunshine.

April 1, 2021

There is fire and there is ice. Fire might be ignoring this virus entirely, and watching an entire society, its economy and its people, crash and burn. Ice, on the other hand, would be freezing everything… cold, hard lockdowns until the virus is extinguished, for as long as it takes. Several months at least. And extinguished along with it, the entire economy… of now healthy — but starving and broke — people.

Neither is a palatable alternative, so we’re stuck navigating a mix of the two… an endless ocean of lukewarm water… where we float around with no destination in sight, hoping to eventually find a shore where we can disembark from this brutal journey.

That being said, actions aside, the *messaging* can’t be lukewarm. It can’t get a little warmer or a little colder. It needs to be decisive, and, around here, it’s not. The result of it is irresponsible parties in Big White… and Whistler… and Surrey weddings… and Yaletown Penthouses. The list goes on.

The lukewarm messaging, along with the lukewarm weather and the lukewarm vaccine rollout has led to this lukewarm attitude… and it’s not good.

I haven’t talked about Chile in a while, so here’s an update: They are the most vaccinated country in the Americas. Their one-jab percentage is 36% (The U.S. is 30%; we’re at 14%). Awesome, right? They must all be out in the streets, partying it up, having a great time, right? Yeah… no. They are, as of today, on a full-on lockdown. Like, full-on… for two weeks.

How did that happen? Many reasons, but a lukewarm attitude to following restrictions is a big part of it. Easing here, easing there. For a while, things were bad. Then they locked it down hard. Then things got better… then they started easing restrictions… then they started making exceptions. The following people are allowed out… caregivers, pharmacy visitors, cab drivers… whatever… the list slowly grew till fully some 5 million people out of the population of 19 million were legally out and about, ostensibly during a lockdown. Not a big deal, because that was when vaccinations were ramping up, and the variants hadn’t arrived. And suddenly, very quickly, with everyone already living like things were back to normal, it’s all gone to hell.

While it’s possible this level of vaccination and nonchalance might have kept up with the original virus, it’s no match for the far-more contagious variants. Accordingly, 5 steps forward has led to 10 steps back. New cases have risen dramatically, and hospitals are near capacity. ICUs are overflowing… and so are the morgues. There can’t be a worse indicator than when the emergency overflow morgues start showing up.

I’ll be honest… I’m not impressed with our lukewarm provincial messaging. Things are kind of good one day, not so good other days. Wishy and washy. Ninety percent of Covid fines are unpaid and, given what we’ve seen with respect to organization around all of this, unlikely to ever be collected. And they are insignificant slaps on the wrist anyway, considering the potential implications. It bothers me greatly that people behave that way, and it bothers me that many do so because they’re just following an example they see all around them. Please don’t do this; please don’t do that. It’s perhaps the biggest downside of being a Canadian during all of this; our inherent politeness doesn’t seem able to impose a degree of harshness that’s truly needed. Give me fire or give me ice. We’re not getting anywhere anytime soon, floating around aimlessly in this vastness of lukewarm water.

But there is some good news… my mom got vaccinated today!

March 26, 2021

The good news with numbers is brief. Yesterday, B.C.’s vaccination rate went from nine point something to ten point something percent. Today, so did Alberta and Ontario… all of which allowed me to change the percentage to one decimal place instead of two. That’s one small step for a decimal point; one giant leap for significant figures as it pertains to reaching the end of this thing. I look forward to Manitoba joining the club soon.

And that concludes the numbers-related good news.

Today, B.C. had over 900 new cases… for the first time since November. What’s also bad is that the new-case growth rate was over 1%… not a particularly good direction for the trend to be heading.

Here are the weekly new-case averages per week, starting 6 weeks ago:

433, 441, 480, 559, 537, 560, 699. There was a nice dip a few weeks ago… right around the time Dr. Henry was calling it a turning point; it’s up to us, yadda yadda… so, how’d we do? There you go.

We’re likely to see the new-case numbers crawl over 1,000 in the next few days… so, to be clear, we’re very much in a 3rd wave… the question is, how bad will it get? Nowhere near as bad as it’d be if we didn’t have improving weather and vaccines. But nowhere near as good as it’d be if we didn’t have variants… and if we’d all properly followed those rules we used to be so good at. Half of that we can’t control… but the other half…

Now it’s Spring Break; people are traveling and doing their own thing. This is how we roll, and for the people who’ve simply “had it” with the pandemic, none of this matters. Ask me in two weeks how much it really matters, but as good or bad as it gets, when it comes to reaching the finish line, it’s not that we’re not running towards it as fast as we can… it’s that we keep pushing it our further. It’s a tough race to figure out when the finish line keeps moving, but it’s even more frustrating when we’re the ones moving it.

Stay tuned for Monday’s numbers… and don’t hold your breath for any radical change in restrictions. If anything, we’re presently going the wrong way.

March 22, 2021

Here’s what seems to be a logical progression… some witty/smart/creative troublemaker comes up with an idea and “puts it out there”. The idea enters an echo chamber of like-minded people who welcome it with open arms. The idea gets tossed around, talked about, enhanced upon… grown in different directions, exaggerated and then commandeered to suit the narrative of whoever is propagating it.

Eventually, the original source of the idea backs away… but that’s now irrelevant. Those who need the idea to exist hold onto it and continue to manipulate it to their heart’s content. When logical people argue against it, they get shot down. When those believers are told it was all made up and whatever was said originally simply isn’t true, they refuse to accept it. When the original guy comes out and says, ”Hey, I was kidding”… believers will assume he’s bought out/paid off/threatened… whatever. Then that person backs away from the mess they’ve created, and all that’s left is a big mess of people believing nonsense they want to believe.

Every single conspiracy theory imaginable can trace its origins to something like this. Some religions as well.

But also… good old common fake news.

The former president of the US made “fake news” a thing. I don’t think any of us had heard those words until Donald Trump began uttering them on an hourly basis, a response to anything that didn’t fit his narrative. And now it’s become the de-facto argument for when people disagree with something to which they have no counterargument.

This follows-up on yesterday’s post, because in reading what people have to say about the AstraZeneca vaccine, one thing is now clear. It was smeared briefly with misinformation, and that smear, for those who want to believe it, will never get polished off. There is no science, no data, no version of facts that can now be presented to someone that’d decided that the AZ vaccine causes blood clots. AZ vaccine causes blood clots in the same way water and fresh air and blinking causes blood clots, but nobody wants to hear that. If vaccines are evil, here’s one more gargantuan piece of evidence. Forget that it’s wrong; that doesn’t matter. Of course, scientists will tell you it’s safe, etc etc.

What can you do? Actually, nothing. I saw a piece of a reported wandering into a restaurant in a very red state; a 90% Trump-voting district. He went in there and asked for a show of hands… “Who’ll be getting the vaccine?”

Not a single hand from the dozens of unmasked people. Not one. He then interviewed a few of them and asked why not… and got the usual answers you’d expect… they’re trying to poison us, they’re trying to control us, they’re trying to kill us… or, it was rushed, it’s not safe, there’s no covid, fake news, etc.
One person was asked the exact question I wanted to hear answered: “If Donald Trump today came out and said to do it… like he did… he got the vaccine, albeit quietly without telling anyone… would you then get the vaccine?”

That particular answer: “No way… why would I listen to Trump? He’s a Liberal New Yorker. Can’t trust him!”.

“But you voted for him.”

“Whatever.”

This is not a “steep uphill”… it’s a vertical, slick and slippery and unclimbable wall. Not even worth trying.

March 11, 2021

Like many things, it depends how you look at it… and that generally leads to a bit of disagreement.

I happened to be reading a news story about a cassette tape that a girl lost while on vacation in Spain. Twenty years later, she saw it in an art gallery, part of a “Sea of Artifacts” exhibit by an artist who’d been documenting plastic pollution and making art out of it.

The girl contacted the artist, and the tape was sent to a professional audio restorer who managed to extract all of the music from it – an eclectic collection ranging from Shaggy and Bob Marley to a bunch of Disney numbers.

So, what’s the story?

Is it about the variety in musical taste of some random 12-year old girl?

Is it about serendipity, synchronicity and the universe?

Is it about the resilience of cassettes? It’s impressive; lost at sea for 20 years, travelling 1,200 miles in rough, salty seas… and it’s still playable. The inventor of the cassette tape died recently (aged 94) – I’m sure he was impressed.

Is it about how plastic is so ridiculously indestructible that we really need to be aware of what we’re dumping into the ocean?

Like usual, it depends who you ask and it depends on their agenda. Today, on the one-year anniversary of the WHO declaring Covid-19 a global pandemic, I’m thinking back to all the news I’ve heard, read and written… the spins I’ve muddled through myself, trying to figure out what’s really going on.

Today, Dr. Bonnie Henry announced a bit of relaxation in restrictions… outdoor gatherings of up to 10 people are now allowed. Also, today, I should point out that our case numbers and ICU admissions are flat… or, keep going up, though not by rates that anyone would call alarming.

It’s been like this from the beginning; somewhat conflicting information that’s left up to interpretation. If you already know the agenda you’re trying to promote, you’ll be able to extract it from there.

I will keep it simple, and this is, as always, only my opinion… outdoor gatherings are probably fine, totally fine. They have been, for a while. Ten people sounds about right, officially, but what does that even mean… if you take over a football field, why not 100. The issue is don’t get too close to someone, and not for too long. You chances of inhaling a lethal viral dose of C19 are next to zero if you’re outdoors. But rules need to be defined, especially because the numbers are not going down… because as straightforward as the rules are, they’re generally not being followed by a significant number of people, and that plays into the math. If 95% of the people stick to the rules and 5% don’t, what can we expect? What if it’s 80/20? What if it’s 50/50?

Once you factor all of that into it, these haphazard-sounding decisions suddenly don’t feel so random or unexpected; they’re not. Like life, it’s all a calculated risk… and the path that’s evident now is one where the numbers don’t get worse, but stay flat or slide downward toward zero… while at the same time slowly and methodically reducing restrictions. It makes sense, though everyone will grab onto the story from different sides and pull in their direction… “numbers aren’t improving”, “see, why did we ever need restrictions”, “I told you it’s ok to get together outside”, “ICU cases keep rising”.

Here’s a generalized suggestion to every single person: Keep doing what you’re doing; we’re all headed in the right direction collectively… you do you, I’ll do me, and we will all eventually hit the finish line. Nobody knows what that percentage split is, but it doesn’t matter… whatever it is, it’s working for us now. If you’ve been sticking to the rules, keep doing so. If you haven’t, I’m sure you won’t start now. And hopefully, that’s all factored into this and it doesn’t matter.

No matter how you look at it, I’m sure we can agree on that.

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March 10, 2021

There’s a lot to learn from looking at the list of countries who managed to secure significant doses of vaccine early in the game, because it begs a lot of questions. Why are they doing so well? Where did they get it from? Why did they get it and not us?

Starting at the top of the list and sorting by Doses… either by “population percentage with at least one dose” or simply “doses per 100 people” – the results are pretty much the same. There, it makes sense to remove the “big” names because the answer is obvious… those that are making the vaccines are using it for themselves as much as they can. The U.S., the U.K, China, Russia. Also remove from there places whose numbers are skewed because of low populations. The Maldives, the Seychelles… tiny populations, mostly vaccinated.

The top of the list now is of course Israel, who was on top of the list before anyone else was removed. They have a population of 9,000,000. They’ve administered 9,000,000 doses. They’re not all first doses, but most are. I saw a picture of a café in Tel Aviv yesterday… and outdoor patio, crowded, no masks, people having a blast. We’ll be there one day… but they’re there now.

How did Israel do it? A pretty sweet deal with Pfizer – one that worked out well for everyone. Lots of data, lots of healthy people. There are plenty of articles to read about how it all came about.

But who’s next on the list now? A terrific outlier to study, as far as I’m concerned.

Chile… and I’m interested because I was born there. Because I have friends and family there. Because I used to travel down there on an almost annual basis, and I know how things work; I know more about doing business with Chile than anyone would ever want to know… which led me to ask the relevant question… who’d they hustle and how’d they do it? Their population is about half of Canada. 22% of those people have had at least one dose. We’re at 5%.

May of 2020 was a bad month down there… 100,000 new infections and almost 1,000 deaths. That’s when they began taking their vaccine plan seriously. Their ministry of health set up meetings with 11 labs around the world, a number that went down to 5 as talks progressed. Internally, it was agreed that when the health regulators of those jurisdictions approved those vaccines, they’d be auto-approved in Chile. To lock in those supplies, meetings were scheduled *in person*. The Chileans flew out to numerous places, including Abu Dabi and the UAE, principal operational hubs for Pfizer and BioNTech. And this is where the Chilean way of business kicked in. I wasn’t in those rooms, but what I know is that those Chileans did not leave without firm deals to receive vaccine; letters of intent, confidentiality agreements… and, probably, agreements not so different from Israel – yes, for sure, we’ll give you the data… we’ll red-line vaccinations… whatever you need… just get us the stuff, AND, if *you* don’t comply with your end of it, there will be hell to pay, as enforced by whatever international laws apply.

I’m speculating a bit and drawing on my knowledge on how things work, and what sort of leverage (the only sort that could possibly be applied) might have worked… because it ultimately worked, and worked well. Very early in the game, Chile was already ahead. By September of last year, Chile was setting up clinical trials for Sinovac and Janssen. Some 3,000 Chileans happily volunteered between October and November. And, for doing so, Chile locked in a $14/dose cost of vaccine and top of the delivery schedule. Chile stuck to their end of it, and the manufacturers have stuck to theirs. Win-win.

Around here, we’re paying $35/dose, when we can get it. Yes, I know – we’ve all read the same news – we will get it all in due course, and just because we keep getting dropped down the list it doesn’t mean anything. Patience, etc. By the time our anger and head-shaking subsides, the pandemic will be over and we’ll have moved on and nobody will care. But allow me to put it in writing; our government let us down. Good intentions are not good enough. Intention to have enough vaccine in a timely manner. Intention to have an infrastructure for booking appointments. Getting up in front a podium and TV cameras isn’t worth anything if you don’t deliver. Nobody is interested in finger pointing and lame excuses, especially how it’s “out of our control”. Your job as our leaders is to find a way to put it into *your* control. Our control. Many governments around the world, with far less resources at their disposal, managed to navigate this process far better.

Ultimately, I’m familiar with the Canadian way of doing business too. The 300,000,000 doses we’ve procured – in the same way Seinfeld “procured” a car reservation in that famous episode – was done with lots of emails, phone calls, Zoom meetings. Whiteboards and PowerPoints. Lawyers and contracts and back-and-forth mark-ups, with nothing in there that could incur any liability. And with nothing to offer in return, very little teeth in those agreements. How can we be sure they’ll hold up their end? It doesn’t matter… and don’t worry about it because with all the “best efforts” language in there, we have zero recourse anyway. Let’s just hope for the best.

Chile started at the finish line. They simply asked, “What is the fastest way to get vaccines into the arms of our population?”… and assigned a group of intelligent resourceful people to just get it done. And they did. Pisco Sours all around. Salúd.

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March 5, 2021

Yesterday’s post generated a lot of interesting responses, as expected… with no real answers, just everyone’s individual opinions. Also as expected, because there’s no right answer.

The summary is probably this: A lot of people, dare I say perhaps the majority, have some negative part of their life that is irrelevant with respect to what they provide to the world. They are brilliant musicians, but they beat up their spouse on occasion. For some people, especially those for whom there’s a personal connection, that’s too much. For others, the quality of their work outshines their personal shortcomings, especially if said shortcomings don’t matter to them. If you’re not trans or couldn’t care less about LGBTQ issues, you’ll keep reading Harry Potter without missing a beat. If you’re sympathetic enough to the cause, perhaps it’ll cause you to think about it. To each, his or her own… and that’s a big, wide chasm… a huge spectrum. There’s no fine line where this falls to one side or the other; it’s very personal – and different – for everyone.

I guess I would similarly draw the line. If it’s important and personal to me, perhaps it crosses that chasm. I sure as hell would not go to a Roger Waters show to watch anti-Semitic propaganda thrown in my face. But I would certainly go to a post-mid-80s Pink Floyd concert headlined by David Gilmour, should that ever happen again. And as far as the music that’s a mix of those two things… yeah, it’s tainted, but its importance to me will never go away.

On a similar note (haha!!), exactly 200 years ago, Beethoven was in the midst of composing his Missa Solemnis, and his 9th symphony… perhaps as close to musical perfection as we’ll ever get. But Ludwig himself… after his brother died, he spent years fighting with his brother’s widow, Joanna. The biggest fight was a custody battle over Karl, his nephew (their son)… and it was vicious… so much so that it led Karl to attempt suicide some years later. Beethoven, as it turns out, wasn’t the most pleasant of fellows… controlling, overbearing… traits that got only worse as he got older and his hearing worsened and his slow lead-poisoning kicked in.

And… I’ll be honest… there’s absolutely nothing that could come to light about Ludwig Van Beethoven that’d ever make me turn off his music. It would be optimistic to think that just because someone can create perfection, they themselves would be so perfect as well… and we can leave it at that. I’m good with that.

And speaking of being optimistic… let’s head into the weekend with some optimistic news: Given the new vaccines, the expected shipment schedules, the extending times between doses and the increasingly good weather, Dr. Bonnie Henry thinks we may start turning the corner to “post-pandemic” as soon as summer. That’d be less than four months before things feel pretty close to normal. I’m good with that too.

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March 1, 2021

I’ve been tuning in to the 3pm news updates pretty regularly, especially on Mondays or Tuesdays, so I can get the real weekend numbers. I used to stick around for the whole update, but find myself checking out early, because, like life itself for so many people these days, it’s the same thing over and over… and, when it’s not, it can be easily summarized in a few brief paragraphs.

Today brought news of the vaccine rollout and the AstraZeneca availability… which is a bit of a game-changer. It’s not recommended for those older than 65, but it’s perfectly and conveniently (room temperature) suited for younger front-line workers, and many of them will be getting the option of that vaccine sooner than later. To find out what the vaccine rollout looks like for you, check the BCCDC for the most up-to-date info… but, to summarize, the older you are, the sooner it’ll be. See you in the lineup in July… hopefully.

But what I want to write about today is a topic that came up in conversation recently… how every event these days held in a public place or on TV or anywhere with a microphone… is preceded by an acknowledgment that the event is occurring on unceded land… and names the relevant Indigenous peoples from whom the land was “improperly” ceded.

To be clear, “unceded” really means “stolen”. This is a vast, complicated topic, and to some extent, around here, steps are being taken to alleviate the damage caused by the “winning” side. In the meantime, it’s interesting to read history from both sides. They tell very different stories.

In Canada or the U.S., you might learn about the great Spanish Conquistador Hernán Cortés, who in the early 16th century undertook dangerous expeditions to the New World, conquered huge lands and brought back great riches. In Mexico, I suspect it’s taught a little differently… that this rapist, pillaging, genocidal maniac showed up with his fancy weapons and illnesses, figured out how to make friends turn on each other, caused the Indigenous people to fight each other… and ultimately conquered the Aztec empire.

You can change the names and dates, but that story has taken place from present-day Alaska to present-day Punta Arenas. And everywhere, there’s a different slant on what happened and how to fix it. A literal and figurative whitewashing of history.

To me, there’s something annoying about standing up and just saying those words, as if that’s enough. Actually, as if it means anything at all. We acknowledge we’re on stolen land, and by saying so that makes us awesome responsible outstanding generous and thoughtful people. Now drop the puck and let’s play some hockey.

This perhaps triggers me more than it should, and here’s why. Many centuries ago, I was a student at SFU… and to pass the time during boring lectures, I would read “The Peak” – the SFU student newspaper which was available for free, everywhere on campus. I’d grab one on my way into the lecture hall, much the way we all used to grab a free “Georgia Straight” on the way to our seats at the Capitol-6 or Vancouver Center theatres.

In the course of a one-hour lecture, I’d get through the entire Peak… every single word… I knew more about the Christy Clark Student Society election scandal than anyone.

Every word… including the entire masthead… contact info, phone number, address (some trailers on campus)… and the final little sentence: “Unfortunately, The Peak is not wheelchair-accessible at present.”

Week after week, month after month, year after year. It bothered me, this grandstanding… look at us, we care enough to be aware of something that might be important to someone… but we won’t do anything about it. I wrote letters, which were never published. I actually tried to take it up with the president: During my tenure at SFU, the president was Dr. William Saywell. There was a thing set up… called “Say it to Saywell” where, ostensibly, you could show up on a Wednesday afternoon in a small room in the AQ… where President Saywell would be available to hear student grievances directly. Except… he never showed up. I tried to go like 10 times, and 10 times he cancelled on short notice. And one day, a sign on the door (and an announcement in The Peak) said it was cancelled forever.

I knew only a few people in wheelchairs and none of them had anything to do with SFU, but it bothered me that much. This wasn’t some great cause I was championing. I was just annoyed at the smug hypocrisy of acknowledging something and not doing anything about it. If it’s worth mentioning, then do something about it. Or shut up. It clearly still bothers me to this day… perhaps my serious issue with people who blow a lot of hot air but never do anything started there.

Stop talking about it like you care, and just get it done. Sit down at the table, listen, and negotiate. Go out and sign some vaccine agreements that actually have some teeth. And just build a freaking ramp.

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February 21, 2021

The numbers will all be accurately updated tomorrow. In the meantime…

There once was a doctor named Henry
Whose gentle words, kind and most friendly,
Said, “Please, just stay home,
This is no time to roam”,
But for many, those words were just merely…

A voice full of spite… so annoying!!
“We’d rather be out, and enjoying
The pubs and the fun,
And the parties and sun,
We’ve just had it with life that’s so boring!!”

The numbers crept up, somewhat slowly
But suddenly jumped… holy moly…
The hospitals slammed,
And the ICUs jammed,
“Oh no”, said the people… “if only…

We’d listened when last we were told
Those words that will never get old:
Be calm, safe and kind,
We can leave this behind,
But it’s not just like some common cold.”

OK… the good news is that the numbers haven’t yet exploded off the chart… but they’re at that point where it could go either way…. and here’s the deal… as long as they stay low, I’ll keep writing about interesting things… like vaccines and science and bitcoins and my life and my dog and whatever else has kept you around, reading this. Maybe I’ll bash Trump a bit more, too… just for old-time’s sake.

And if numbers go up, you will all instead be subjected to more terrible poetry. As per above, it’s up to you. You’ve been warned. Don’t make me do it. Please.

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February 15, 2021

Given the prevalence of anti-vaxx insanity and the fact that this virus continues to mutate, chances are it’ll be around for a long time. Perhaps forever. But that’s not the end of the world, because measles is also around, and nobody worries too much about it. The vast majority of people are vaccinated against it, and even if you get it, there’s a well-known treatment plan that’ll lessen the symptoms and help you get through it.

Similarly, for all the talk we have about C19 vaccines, let’s not forget that a lot has been learned about treatment, and a lot of drugs have been (and continue to be) developed specifically for that.

Initially, some already-existing drugs were found to have some positive effects. Dexamethasone, Remdesivir and Baricitnib among them, with varying degrees of success. Therapies involving convalescent plasma and monoclonal antibodies have been found to be very effective. “Potshots” with other existing drugs, such as Interferon and Tamiflu, have not been so successful. Antibiotics, drugs used to combat gout, other anti-virals… the list goes on and grows daily, as more data is collected and analyzed.

Two recent additions to the list are interesting.

First is news from Israel, who have been leading the charge with vaccinations — over 70% (!) of their population have received at least one dose — they’ve developed a drug for use in moderate or worse cases, and the early results couldn’t be more encouraging. Thirty people entered the hospital in relatively serious condition, and thirty people emerged cured… twenty-nine of them within three to five days. The drug, EXO-CD24, specifically fights the cytokine storm, the likeliest C19 complication that leads to death. Good numbers for a Phase-1 study. Onward.

Second is the locally-developed and hard-to-pronounce Bamlanivimab, which is beginning clinical trials locally… though it’s already been used on more than 125,000 patients in the U.S.

The one-two punch of vaccines and effective treatment is what will eventually return the world to normal… when everyone is convinced enough that they’re unlikely to get it, but even if they do, it’ll be no big deal. Given where our minds are these days, that seems like a big leap… but such was the case before antibiotics showed up. We take antibiotics for granted… oh, a little infection, no big deal… take these little pills a few times a day for a week and you’ll be fine. A hundred years ago, that little infection may well have killed you.

One day, catching some variant of C19 may be viewed with the same sort of novelty as catching Bubonic Plague… it’s rare, it’s out there, but… most importantly… it’s treatable and it’s curable. Interestingly, we’re probably at that point today, at least from a scientific point of view. Further tests will either confirm or disqualify that statement… but, either way, today’s issue isn’t the science as much as it is logistics and distribution.

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